BDBM403822 (2S,5R)-5-(2-chlorophenyl)-1-(3-hydroxy-5-(trifluoromethyl)benzoyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 48::US10781171, Compound 48::US11072582, Compound 48

SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)c1cc(O)cc(c1)C(F)(F)F)c1ccccc1Cl

InChI Key InChIKey=XDVJZGWPTVURKG-CVEARBPZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 403822   

TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM403822((2S,5R)-5-(2-chlorophenyl)-1-(3-hydroxy-5-(trifluo...)
Affinity DataEC50: >1.00E+3nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM403822((2S,5R)-5-(2-chlorophenyl)-1-(3-hydroxy-5-(trifluo...)
Affinity DataEC50: >1.00E+3nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM403822((2S,5R)-5-(2-chlorophenyl)-1-(3-hydroxy-5-(trifluo...)
Affinity DataEC50: >1.00E+3nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent