BDBM405108 1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)phenyl]methyl} carbamoyl)-1H-1,2,3-triazol-1-yl] butyl}-N-[(1S)-2-hydroxy-1- phenylethyl]-1H-1,2,3-triazole-4- carboxamide::US10344025, Example 452::US11370786, Example 452

SMILES OC[C@@H](NC(=O)c1cn(CC(F)CCn2cc(nn2)C(=O)NCc2cc(OC(F)(F)F)ccc2F)nn1)c1ccccc1

InChI Key InChIKey=CPPWPBVFKORBIK-WBPHRXDCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405108   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM405108(1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM405108(1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...)
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent