BDBM405110 1-[2-fluoro-4-(4-{[(2- fluorophenyl)methyl]carbamoyl}- 1H-1,2,3-triazol-1-yl)butyl]-N-{[4- (trifluoromethyl)pyridin-2-yl] methyl}-1H-1,2,3-triazole-4- carboxamide::US10344025, Example 454::US10344025, Example 464::US11370786, Example 454
SMILES FC(CCn1cc(nn1)C(=O)NCc1ccccc1F)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F
InChI Key InChIKey=HOPDPALXTHXNNF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 405110
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: <100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair