BDBM410013 US10370339, Example 2-20

SMILES COC(=O)CCc1ccc2n([C@@H]3C[C@H](C)CC[C@H]3C(C)C)c(Nc3ccc(cc3)C(C)C)nc2c1

InChI Key InChIKey=ABOGRSYSLXIKNP-AHCMPFEKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410013   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM410013(US10370339, Example 2-20)
Affinity DataIC50:  130nMAssay Description:Mutant IDH1 R132H Biochemical Assay mIDH1 catalyzes the NADPH-dependent reduction of alpha-ketoglutarate (a-KG) to (2R)-2-hydroxyglutarate (2-HG). NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent