BDBM412198 US10398703, Compound 35::US10966987, Compound 35

SMILES COc1cc2c(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)ncnc2cc1OCCCC(=O)N1CCC2(COC2)CC1

InChI Key InChIKey=AGPTZIZTIWWLJY-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412198   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412198(US10398703, Compound 35 | US10966987, Compound 35)
Affinity DataKd:  1.30E+3nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412198(US10398703, Compound 35 | US10966987, Compound 35)
Affinity DataKd:  1.30E+3nMAssay Description:A competition binding assay (DISCOVERX KINOMESCAN™) was used to measure the ability of a compound to compete for binding of an immobilized adenosine ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent