BDBM412340 US10399958, Compound 2e
SMILES C\C(CCC(O)=O)=C/COc1ccccc1Cn1c(C)cnc1-c1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=LKBNNCNNGBRSKP-GHRIWEEISA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 412340
Affinity DataEC50: 0.200nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Modulator activity at GAL4-fused human PPARgamma LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: 2.29E+3nMAssay Description:Modulator activity at GAL4-fused human PPARalpha LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 0.300nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Ligand Info