BDBM414109 (R)-7-methyl-4-(1- (methylsulfonyl)piperidin- 4-yl)-6-(6-(2,2,2-tri- fluoroethoxy)-1H- pyrrolo[2,3-b]pyridin-4- yl)-5,6,7,8-tetrahydro- pyrido[4,3-d]pyrimidine::US10421765, Example 96::US10745420, Example 96
SMILES C[C@@H]1Cc2ncnc(C3CCN(CC3)S(C)(=O)=O)c2CN1c1cc(OCC(F)(F)F)nc2[nH]ccc12
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414109
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 321nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 321nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair