BDBM414465 N-{6-(2-Hydroxypropan-2-yl)-2-[(3S)-tetrahydrofuran-3-yl]-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide::US10435396, Example 36

SMILES CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CCOC1

InChI Key InChIKey=KWISQFLSAWNNRM-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414465   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414465(N-{6-(2-Hydroxypropan-2-yl)-2-[(3S)-tetrahydrofura...)
Affinity DataIC50:  28nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent