BDBM414467 N-{2-[(3S)-1,1-Dioxidotetrahydrothiophen-3-yl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide::US10435396, Example 41
SMILES CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CCS(=O)(=O)C1
InChI Key InChIKey=SVXGLJRWMXEQBR-ZDUSSCGKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 414467
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiegesellschaft
US Patent
Bayer Pharma Aktiegesellschaft
US Patent
Affinity DataIC50: 16nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair