BDBM414480 2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-5-({[6-(trifluoromethyl)pyridin-2-yl]carbonyl}amino)-2H-indazole-6-carboxamide::US10435396, Example 56

SMILES CC(C)(O)CCN1CCC(CC1)n1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(N)=O

InChI Key InChIKey=KQJGNHRGEMAORY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414480   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414480(2-[1-(3-Hydroxy-3-methylbutyl)piperidin-4-yl]-5-({...)
Affinity DataIC50:  4nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent