BDBM415401 Intermediate 1-1-1 (4-hydroxy-6,6-dimethyl-2-oxo-N-phenyl-1,2,5,6-tetrahydropyridine-3-carbothioamide)::US10428063, Example 1

SMILES CC1(C)CC(O)=C(C(=S)Nc2ccccc2)C(=O)N1

InChI Key InChIKey=GYGGFEHHGMQBBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415401   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415401(Intermediate 1-1-1 (4-hydroxy-6,6-dimethyl-2-oxo-N...)
Affinity DataIC50:  11.6nMAssay Description:In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent