BDBM415414 Example 14 (N-{4-[4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide)::US10428063, Example 14::US20230322767, Example No. 14 WO 2016/120196::US20230339939, WO 2016/120196, Example 14::WO 2016/120196, Example 14

SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2CCNC(=O)c2c1Nc1ccccc1

InChI Key InChIKey=OEXTZXWPZXNIIH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 415414   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM415414(Example 14 (N-{4-[4-oxo-3-(phenylamino)-4,5,6,7-te...)
Affinity DataIC50:  104nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM415414(Example 14 (N-{4-[4-oxo-3-(phenylamino)-4,5,6,7-te...)
Affinity DataIC50:  20.3nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent