BDBM420041 US10487084, Compound Ib-02

SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(nc3)-c3csc(CN)c3)c2n1

InChI Key InChIKey=LRTMQBKGDGYHTB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420041   

TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  7.55nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  52nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent