BDBM420217 US10485800, Cmpd ID FS::US10485800, Example 173

SMILES CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ncc5c4)c3c2)CC1

InChI Key InChIKey=RWJSBHSWVMKBER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420217   

TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM420217(US10485800, Cmpd ID FS | US10485800, Example 173)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of TNIK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM420217(US10485800, Cmpd ID FS | US10485800, Example 173)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent