BDBM420242 US10485800, Cmpd ID Preparation of 5-(4-((1H-imidazol-1-yl)methyl)phenyl)-3-(1H-indol-5-yl)-1H-pyrrolo[2,3-b]pyridine ::US10485800, Example 190

SMILES C(c1ccc(cc1)-c1cnc2[nH]cc(-c3ccc4[nH]ccc4c3)c2c1)n1ccnc1

InChI Key InChIKey=XUKRMVRUDPPBHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420242   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM420242(US10485800, Cmpd ID Preparation of 5-(4-((1H-imida...)
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent