BDBM423272 (Racemic Mixture)::US10501451, Example 4::US10954225, Example 4

SMILES Cc1ccc(CN2OCCC(N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1

InChI Key InChIKey=TYMSZYLMXQIIJM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423272   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423272((Racemic Mixture) | US10501451, Example 4 | US1095...)
Affinity DataKi:  5.49nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423272((Racemic Mixture) | US10501451, Example 4 | US1095...)
Affinity DataKi:  5.49nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent