BDBM425307 US10519177, Compound P-0186::ethyl 2-[6-(3,5-dimethylisoxazol-4-yl)-3-(1- methylpyrazol-4-yl)pyrrolo[3,2-b]pyridin-1- yl]-2-phenyl-acetate

SMILES CCOC(=O)C(c1ccccc1)n1cc(-c2cnn(C)c2)c2ncc(cc12)-c1c(C)noc1C

InChI Key InChIKey=VPTNGNUXXCWXIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425307   

TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425307(US10519177, Compound P-0186 | ethyl 2-[6-(3,5-dime...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent