BDBM425352 4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-3-[1-(2,2,2- trifluoroethyl)pyrazol-4-yl]pyrrolo[3,2- b]pyridin-6-yl]-3,5-dimethyl-isoxazole::US10519177, Compound P-0257::US10519177, Compound P-0305

SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3CC(F)(F)C3)c2c1)-c1cnn(CC(F)(F)F)c1

InChI Key InChIKey=ZVROERWTIKLVHP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 425352   

TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425352(4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425352(4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425352(4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425352(4-[1-[dideuterio-(3,3- difluorocyclobutyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent