BDBM425414 4-[3-iodo-1-(pyrimidin-2- ylmethyl)pyrrolo[3,2-b]pyridin-6-yl]- 3,5-dimethyl-isoxazole::US10519177, Compound P-0319

SMILES Cc1noc(C)c1-c1cnc2c(I)cn(Cc3ncccn3)c2c1

InChI Key InChIKey=BPAUVPPGYFOHKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425414   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425414(4-[3-iodo-1-(pyrimidin-2- ylmethyl)pyrrolo[3,2-b]p...)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425414(4-[3-iodo-1-(pyrimidin-2- ylmethyl)pyrrolo[3,2-b]p...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent