BDBM425416 3,5-dimethyl-4-(1-[(1,4,4- trifluorocyclohexyl)methyl]-3-[1- (2,2,2-trifluoroethyl)pyrazol-4- yl]pyrrolo[3,2-b]pyridin-6-yl]isoxazole::US10519177, Compound P-0321

SMILES Cc1noc(C)c1-c1cnc2c(cn(CC3(F)CCC(F)(F)CC3)c2c1)-c1cnn(CC(F)(F)F)c1

InChI Key InChIKey=LQOMVCGXZJVIJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425416   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425416(3,5-dimethyl-4-(1-[(1,4,4- trifluorocyclohexyl)met...)
Affinity DataIC50:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425416(3,5-dimethyl-4-(1-[(1,4,4- trifluorocyclohexyl)met...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent