BDBM425463 3-[1-[dideuterio-(4,4- difluorocyclohexyl)methyl]-6-(3,5- dimethylisoxazol-4-yl)pyrrolo[3,2- b]pyridin-3-yl]prop-2-yn-1-ol::US10519177, Compound P-0370

SMILES CC1=CC=C(C)C1c1cnc2c(cn(CC3CCC(F)(F)CC3)c2c1)C#CCO

InChI Key InChIKey=XOWHAYQRFGQZPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 425463   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425463(3-[1-[dideuterio-(4,4- difluorocyclohexyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-164](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM425463(3-[1-[dideuterio-(4,4- difluorocyclohexyl)methyl]-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Binding of compounds of formula (I) with bromodomain 2, 3 4 was assessed using Alphascreen binding assay. The inhibition of the interaction between b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent