BDBM426369 US10526325, Compound A45::US10829489, Compound A45

SMILES C[C@@](O)(C(=O)N1CCc2c(C1)ncn2-c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=VEKVAVGNILVOKU-OAHLLOKOSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426369   

LigandPNGBDBM426369(US10526325, Compound A45 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM426369(US10526325, Compound A45 | US10829489, Compound A4...)
Affinity DataKd: <300nMAssay Description:The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent