BDBM427556 3-({[4-(2-amino-1,3- benzothiazol-4-yl)-2- sulfamoyl-3-(1H- tetrazol-5- yl)phenyl]sulfonyl} amino)-N,N,N- trimethylpropan-1- amimum trifluoroacetate::US10544130, Example 392

SMILES C[N+](C)(C)CCCNS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O

InChI Key InChIKey=SJTLDCMGGRCPJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 427556   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM427556(3-({[4-(2-amino-1,3- benzothiazol-4-yl)-2- sulfamo...)
Affinity DataIC50:  0.221nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase()
Merck Sharp & Dohme

US Patent
LigandPNGBDBM427556(3-({[4-(2-amino-1,3- benzothiazol-4-yl)-2- sulfamo...)
Affinity DataIC50:  0.101nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM427556(3-({[4-(2-amino-1,3- benzothiazol-4-yl)-2- sulfamo...)
Affinity DataIC50:  0.0320nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent