BDBM429372 MPI2::med.21724, Compound 43

SMILES Fc1cc(Cl)ccc1\C=C\C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O

InChI Key InChIKey=HXAHMXYAYHWWRI-ZCTWNQIISA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 429372   

TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandPNGBDBM429372(MPI2 | med.21724, Compound 43)
Affinity DataKi:  101nM IC50:  103nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM429372(MPI2 | med.21724, Compound 43)
Affinity DataIC50:  200nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
University of Bonn

LigandPNGBDBM429372(MPI2 | med.21724, Compound 43)
Affinity DataIC50:  1.70E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed