BDBM429414 4-(furan-2-yl)-2-((2-hydroxy- 1-phenylethyl)thio)-6- (thiophen-2-yl)nicotinonitrile::US10548313, Formula IIb-iv::US11375716, Formula IIb-iv

SMILES OCC(Sc1nc(cc(-c2ccco2)c1C#N)-c1cccs1)c1ccccc1

InChI Key InChIKey=UZDZTMXTOFHZEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 429414   

TargetAcetyl-CoA carboxylase(Corn smut fungus)
Monsanto Technology

US Patent
LigandPNGBDBM429414(4-(furan-2-yl)-2-((2-hydroxy- 1-phenylethyl)thio)-...)
Affinity DataIC50:  2.18E+3nMAssay Description:In order to effectively screen out non-specific modulators of pyruvate kinase and lactate dehydrogenase (the coupled portion of the reaction), a PK/L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase(Zea mays)
Monsanto Technology

US Patent
LigandPNGBDBM429414(4-(furan-2-yl)-2-((2-hydroxy- 1-phenylethyl)thio)-...)
Affinity DataIC50:  2.18E+3nMAssay Description:Ustilago maydis acetyl CoA carboxylase (ACCase) was cloned, expressed, and purified as described (Weatherly et al, Biochem. J., 2004) and the test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent