BDBM4296 (2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile::Tyrphostin deriv. 29

SMILES Oc1ccc(\C=C(/C#N)C(=O)c2ccccc2)cc1O

InChI Key InChIKey=QBKFKKGORMOFFU-MDWZMJQESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4296   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4296((2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-eneni...)
Affinity DataIC50:  1.30E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed