BDBM430500 (R)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide and (S)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide::US10556902, No 108::US10556902, No 109::US11612599, Compound 109

SMILES CC(N1CCN(CC1)c1nnc(NC(C)=O)s1)c1ccc2CCOc2c1

InChI Key InChIKey=WIEMWLGSWIIWEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 430500   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM430500((R)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)p...)
Affinity DataIC50:  5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM430500((R)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)p...)
Affinity DataIC50: <50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM430500((R)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)p...)
Affinity DataIC50:  5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM430500((R)—N-(5-(4-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)p...)
Affinity DataIC50: <50nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent