BDBM430550 US10556914, Example 38

SMILES COc1ccc(cc1-c1nn(C(C)c2ccc(Cl)cc2)c(=O)c2c(C)noc12)C(=O)N(C)C

InChI Key InChIKey=XIIRTDMWGYRZQV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430550   

TargetGamma-aminobutyric acid type B receptor subunit 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM430550(US10556914, Example 38)
Affinity DataEC50:  643nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent