BDBM431547 US10550105, Example 492::US10870641, Example 492::US11014913, Example 492

SMILES FC(F)(F)c1c(cn[nH]c1=O)N1Cc2cccc(OCCNCCC(=O)N3CCN(CC3)c3ccc(cn3)C#N)c2C1

InChI Key InChIKey=NCDMNLWWDIGTNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 431547   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM431547(US10550105, Example 492 | US10870641, Example 492 ...)
Affinity DataIC50: <100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM431547(US10550105, Example 492 | US10870641, Example 492 ...)
Affinity DataIC50: <100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM431547(US10550105, Example 492 | US10870641, Example 492 ...)
Affinity DataIC50: <100nMAssay Description:Displacement of Probe A, a biotinylated probe binding to the TIPARP active site, was measured using a time-resolved fluorescence energy transfer (TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent