BDBM431887 3-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azabicyclo[3.1.0]hexan-4- yl)ethynyl)phenyl)imidazo[1,5-a]pyridine-1- carboxamide::US10550117, Compound 3

SMILES CN1[C@@H]2C[C@@H]2[C@@](O)(C#Cc2cccc(c2)-c2nc(C(N)=O)n3ccccc23)C1=O

InChI Key InChIKey=ABXMJYQXZPZSMF-JIGPKXGUSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 431887   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM431887(3-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azab...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent