BDBM431890 5-amino-2-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3- oxo-2-azabicyclo[3.1.0]hexan-4- yl)ethynyl)phenyl)thiazole-4-carboxamide::US10550117, Compound 6

SMILES CN1[C@@H]2C[C@@H]2[C@@](O)(C#Cc2cccc(c2)-c2nc(C(N)=O)c(N)s2)C1=O

InChI Key InChIKey=AUFXFAGNXHROSG-IUUKEHGRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 431890   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM431890(5-amino-2-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3- ox...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent