BDBM432087 US10577308, Compound 558

SMILES Cc1cccc(C)c1OCCCNCc1cccc(c1)-c1cncnc1

InChI Key InChIKey=UUJCWXBORMXXGI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 432087   

TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  1.20E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  400nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  300nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  300nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  200nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
The Florey Institute

US Patent
LigandPNGBDBM432087(US10577308, Compound 558)
Affinity DataIC50:  200nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent