BDBM433820 US10562878, Compound 231 E1::US10562878, Compound 231 E2

SMILES CNC(C)C1(CCC(O)CC1)c1ccc2ccccc2c1

InChI Key InChIKey=ADWAGSCYZKTLSE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 433820   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  136nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433820(US10562878, Compound 231 E1 | US10562878, Compound...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent