BDBM43509 2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidine::4-(2-methoxyphenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine::MLS000519881::SMR000130296::US11725000, Compound 51::cid_4655086

SMILES COc1ccccc1-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=MABPZKJJTICMDB-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43509   

TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43509(2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50:  3.18E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43509(2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50: >1.86E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute of Biological Sciences, Beijing

US Patent
LigandPNGBDBM43509(2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataEC50:  5.50E+3nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43509(2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50:  3.63E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM43509(2-mesyl-4-(2-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay