BDBM435283 US10568876, Example 46::ethyl 5-(2-(tert-butylcarbamoyl)-8- (((trans)-2- phenylcyclopropanecarboxamido) methyl)-1,2,3,4-tetrahydroisoquinolin-5- yl)nicotinate (mixture of 2 isomers)

SMILES CCOC(=O)c1cncc(c1)-c1ccc(CNC(=O)C2C[C@H]2c2ccccc2)c2CN(CCc12)C(=O)NC(C)(C)C

InChI Key InChIKey=CYIXPMIDGDCYSG-MBMZGMDYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435283   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435283(US10568876, Example 46 | ethyl 5-(2-(tert-butylcar...)
Affinity DataIC50:  0.660nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent