BDBM438680 US10618903, Example 247

SMILES CC(C)Cn1cc(Nc2cc(ncc2C(=O)NC[C@@H](F)C(C)(C)O)-c2cnn3cc(Cl)cnc23)cn1

InChI Key InChIKey=ZSYNGUVZDFUNBQ-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438680   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM438680(US10618903, Example 247)
Affinity DataIC50:  2nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent