BDBM438729 (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 3-methyl-4-propionylpiperazin-1-yl]-4- pyridin-2-yl-4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazine::US10618910, Example 8

SMILES CCC(=O)N1CCN(C[C@H]1C)c1nc2ccc(-c3c(C)noc3C)c3OC[C@H](c4ccccn4)n1c23

InChI Key InChIKey=DGRMYTISESUMFZ-OPAMFIHVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438729   

TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438729((4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 3-meth...)
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM438729((4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[(3S)- 3-meth...)
Affinity DataIC50: <25nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent