BDBM438749 21-isopropyl-23-methyl-21H,51H-10-oxa-3-aza- 2(5,7)-pyrazolo[4,3-b]pyridina-1(3,2)- pyridina-5(5,1)-pyrazolacyclodecaphane::US10618913, Example 9

SMILES CC(C)n1nc(C)c2nc-3cc(NCc4ccnn4CCCCOc4ncccc-34)c12

InChI Key InChIKey=TZLKATCVHPXNFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438749   

LigandPNGBDBM438749(21-isopropyl-23-methyl-21H,51H-10-oxa-3-aza- 2(5,7...)
Affinity DataIC50:  53nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM438749(21-isopropyl-23-methyl-21H,51H-10-oxa-3-aza- 2(5,7...)
Affinity DataIC50:  56nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM438749(21-isopropyl-23-methyl-21H,51H-10-oxa-3-aza- 2(5,7...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent