BDBM438853 3-((1R,5S,9R)-3-((1R,3r,5S)-6,6-difluorobicyclo[3.1.0]hexan-3-yl)-9-methoxy-3-azabicyclo[3.3.1]nonan-9-yl)benzamide hydrochloride::US10604489, Compound 17::US11180455, Compound 200

SMILES COC1(C2CCCC1CN(C2)[C@@H]1C[C@H]2[C@@H](C1)C2(F)F)c1cccc(c1)C(N)=O

InChI Key InChIKey=KXXOVXXUFUENAW-OEMLNSRHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438853   

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM438853(3-((1R,5S,9R)-3-((1R,3r,5S)-6,6-difluorobicyclo[3....)
Affinity DataKi: <1nMAssay Description:Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM438853(3-((1R,5S,9R)-3-((1R,3r,5S)-6,6-difluorobicyclo[3....)
Affinity DataKi: <1nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM438853(3-((1R,5S,9R)-3-((1R,3r,5S)-6,6-difluorobicyclo[3....)
Affinity DataKi: <1nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent