BDBM439330 (S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)-3-phenylpropanamido)benzoic acid::US10633375, Compound No. 9::US11084808, Compound 9

SMILES CCC(=O)c1ccc(Cl)cc1-c1cc(=O)n(cc1OC)[C@@H](Cc1ccccc1)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=WTMQPGKZTXMNAQ-SANMLTNESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439330   

TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439330((S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy...)
Affinity DataIC50:  14nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439330((S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy...)
Affinity DataIC50:  14nMAssay Description:Test Example 1: Biological Activity of the Compounds of the Present Invention onThe Inhibition of Factor XIa Detected by Absorption Photometry1. Expe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent