BDBM440290 US10633389, Example 642-1a::US20230279020, Example 642-1a

SMILES CCOC(=O)N1CCN(CC1)c1nc(nc(NC2CCOCC2)c1C)-c1cccc(OCC(O)CNC)c1

InChI Key InChIKey=OAOOUSYSARBZJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 440290   

TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM440290(US10633389, Example 642-1a | US20230279020, Exampl...)
Affinity DataIC50:  2.00E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM440290(US10633389, Example 642-1a | US20230279020, Exampl...)
Affinity DataIC50:  2.00E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent