BDBM441813 US10647665, Example 1-2::US1085105, Example I-2

SMILES CCS(=O)(=O)c1ccc(CNC(=O)Nc2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=MRSGUEYLLHNWOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 441813   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

US Patent
LigandPNGBDBM441813(US10647665, Example 1-2 | US1085105, Example I-2)
Affinity DataIC50:  2.75E+4nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

US Patent
LigandPNGBDBM441813(US10647665, Example 1-2 | US1085105, Example I-2)
Affinity DataIC50:  2.75E+5nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
In DepthDetails US Patent