BDBM441837 US10647665, Example 1-23::US10851050, Example I-23
SMILES OC(=O)Cc1ccc(CNC(=O)Nc2ccc(cc2)-c2ccccc2)cc1
InChI Key InChIKey=JGINBPKDFJSKCS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 441837
Affinity DataIC50: 2.75E+5nMAssay Description:1. Preparation of RORgamma Buffer Solution10 mL of DTT and 100 mL buffer solution were gently mixed together and ready to use.2. Preparation of Compo...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inverse agonist activity at human RORgammat assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitment measured after 60 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+4nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair