BDBM444509 (S)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)- 3-chloro-N-(thiazol-2-yl)benzenesulfonamide::US10662184, Example 80

SMILES CN([C@H]1CCN(C1)c1ccccc1)c1ccc(cc1Cl)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=GRQUJGHVLFJTIA-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444509   

TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM444509((S)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)- 3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM444509((S)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)- 3-...)
Affinity DataIC50:  124nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent