BDBM445090 (2S,4S)-4-fluoro-2-(4-(5-(trifluoromethyl)-1H-pyrazol-4-yl)indoline-1-carbonyl)pyrrolidine-1-carbonitrile::US10669234, Example 29

SMILES F[C@H]1C[C@H](N(C1)C#N)C(=O)N1CCc2c1cccc2-c1cn[nH]c1C(F)(F)F

InChI Key InChIKey=AHCBJXSHVXHGHF-BONVTDFDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445090   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics

US Patent
LigandPNGBDBM445090((2S,4S)-4-fluoro-2-(4-(5-(trifluoromethyl)-1H-pyra...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent