BDBM445114 (S)-N-(4-(2-chlorophenyl)- thiazol-2-yl)-1-cyano-N- methylpyrrolidine-2- carboxamide::US10669234, Example 53::US11319287, Example 53
SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1nc(cs1)-c1ccccc1Cl
InChI Key InChIKey=KTBZQJVLCMGVDY-AWEZNQCLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 445114
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics
US Patent
Mission Therapeutics
US Patent
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Mission Therapeutics
US Patent
Mission Therapeutics
US Patent
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair