BDBM447493 US10689357, Example 30
SMILES COc1ccc(cc1F)-c1ccc(cc1)S(=O)(=O)N[C@H]1C[C@H](C1)N=C=S
InChI Key InChIKey=HMQOATSGVLIACK-GASCZTMLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 447493
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human NAAA using N-(4-methyl coumarin)-palmitamide as fluorogenic substrate preincubated for 90 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair