BDBM448674 N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)phenyl)-5- (pyridin-4-yl)furan-2-carboxamide::US10696661, Compound 27

SMILES Clc1ccc(N2CCN(Cc3cocn3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1

InChI Key InChIKey=STOGHDINYGFDGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448674   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

US Patent
LigandPNGBDBM448674(N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl...)
Affinity DataIC50:  8.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent