BDBM448696 N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)-5-(tetrahydro-2H-pyran-4-yl)furan- 2-carboxamide::US10696661, Compound 44

SMILES Cc1ccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)C2CCOCC2)C(F)(F)F)o1

InChI Key InChIKey=IIOMUMPSUGETRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448696   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

US Patent
LigandPNGBDBM448696(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)
Affinity DataIC50:  3.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent