BDBM448697 N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)-5-methylfuran-2-carboxamide::US10696661, Compound 45

SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccoc2)CC1)C(F)(F)F

InChI Key InChIKey=YVIPYWOQAQZMSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448697   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

US Patent
LigandPNGBDBM448697(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)
Affinity DataIC50:  1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent